Lull Raka shows how to protect ourselves from the new version of the Coronavirus

The new variable has already been confirmed in Great Britain, while reportedly circulates much faster.

This new version of SARS-CoV-2, referred to as SARS-CoV-2 VUI 202012/01 (“Under Investment”, 2020, month 12, variant 01), has been identified through genomic sequences in the United Kingdom. This new version is determined by multiple mutations in the protein of the virus, which are located on its surface and have the shape of cymbals or stings (delecions 69-70, 144, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H) and mutations in other genome regions.”, Raka writes.

This is his full status:

V SRS-COV-2 RIANT

EPIDEMIOGIA

Over the past few weeks, Great Britain has faced a rapid increase in cases with COVID-19, which was accompanied by the appearance of a new version in this area in November 2020. The reported cases of COVIDD-19 in connection with the new version have focused on Kent and wider South East England.

This new version of SARS-CoV-2, referred to as SARS-CoV-2 VUI 202012/01 (“Under Investment”, 2020, month 12, variant 01), has been identified through genomic sequence in the United Kingdom. This new version is determined by multiple mutations in the protein of the virus, which are located on its surface and have the shape of cymbals or stings (delecions 69-70, 144, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H) and mutations in other genomic regions.

Such cases have also been reported in Denmark (9 cases), Belgium (4 cases), and the Netherlands in Australia on one occasion.

HOW CRIUE WARIANT BUT I W IRUST SARS-COV-2?

Still no full details of the pathogen of these changes are known, but there are some initial assumptions of scientists.

A possible explanation for the release of the new version is the prolonged infection of SARS-CoV-2 into a single patient, potentially with reduced immunization. Such prolonged infection can lead to the accumulate of mutations called “escape mutations”.

Another possible explanation may be the process of adapting the virus to a different species of sensitive animals and then passing on to humans. This led to the appearance of a version with multiple mutations of X-ray proteins (including the R45D Y453F mutation and the elimination of 69-70) in Denmark during the broadcast among mustelid group animals. Great Britain has reported it E CDC and O Regional Office BSH for Europe that there is no clear epidemiological link between the new variant and the animals.

Finally, it is also possible that the new version has been shown through circulation in countries that are unable to make genetic sequences.

WHAT AFFAIRS SUFFECTIONS WRITER IN SURY E MAN?

Current information is based on limited data and assessment will be updated as soon as new scientific information and details are provided.

Viruses constantly differ through mutation, and the appearance of a new version is an expected phenomenon. SARS-CoV-2 is ARN virus and mutations occur as natural phenomena during the virus's multiplying. There have already been nearly 4,000 mutations in the X-ray protein, but only a very small number of them have had significance in changing the virus.

Most mutations in the virus will not give any selective advantage to the virus. However, some mutations or mutation combinations can provide the virus with a selective advantage, such as increased transmission through increased connections with receptors.

A YOU CAN PRAY KY VARORANT?

The first analyses in the UK suggest the new version spread much faster, increasing the reproductive number (R) by 0.4 or a widespread increase of up to 70%.

This new version has appeared at a time of the year when family contacts, social contacts, and travel are dramatically increased because of the holiday season.

A DO YOU AFFECT TO SARS-COV-2?

Great Britain reports that mutation through delegation 69-70 in the new version's grebe protein has produced negative PCR results from the test of the S- RT- PCR in some labs.

lab tests using gene S are not widely used in diagnostics. Focus only on finding S for primary detection of SARS-CoV-2 infection using RT- The PCR is not recommended because mutations are more likely to occur in this gene.

A CAN IT SHOW THE ENVIRONMENT?

Information available regarding the severity of the new version of the virus is limited. Thus far it has not been reported that this version has a higher rate of disease, mortality, or affecting more specific groups. VUI 202012/01 variation cases have been identified mainly in people younger than 60.

Mutations that make the virus more efficient are not meant to make it more dangerous. Right now, there's no evidence that this option is clinically more dangerous than preemptive variants. But the assessment is challenged by the fact that most cases are reported to people under 60 who are usually less likely to have serious symptoms.

None of the previously described variants of SARS-CoV-2 has been shown to cause the severity of infection to rise. Like. The D614G version that caused the biggest spread during the summer has not been the cause of the most severe clinical display of disease.

A CAN AFFECT IN THE RECENT What about RI-INFEKES?

Based on the number and location of X-ray mutations, it seems likely that you will see a reduction in antibody neutralization, but there is still no evidence that there is an impact resulting in increased risk of re-infectation.

A IT WILL NEED IN EFEKTIV ITET IN THE VACSINE?

The new version of the virus exhibits mutations in the blood protein, including the location of the receptor. Most of the new vaccines are based on the sequence of green proteins.

But vaccines produce antibodies to many regions of the X - ray protein, so it is less reliable that a single change would make the vaccine less efficient.

It is imperative to monitor the changes in this protein among the surrounding SARS-CoV-2 types and assess possible antigenic changes. It will be important to oversee the effectiveness in the field of COVID-19 vaccines in use.

WHAT MASASAS BEAST DON'T FOR PRENDAL?

The government of Scotland announced a stop to travel between Scotland and the rest of the United Kingdom from December 26th. The Netherlands issued a ban from the UK of 20,12,2020, while Belgium banned the UK's flight and train from 20.12,2020.

Measures needed that are taken at the right time in trying to prevent and control the spread of the new version:

• People with any epidemiological connection to cases with the newest version of the virus or travel stories in affected areas must be immediately identified to test, isolated, and follow their contacts.

• To strictly respect precautions.

• Avoid travel from the affected area or to the affected area and avoid unescial social activities.

• Labs should review PCR performance and avoid diagnosis based solely on genius S.

• Suspected cases of COVID re-infectation-19 should be monitored, making their immediate sequence.

• With the implementation of the vaccine, a close monitoring of individuals vaccinated COVID-19 must be provided to identify possible vaccine failures.