Children to be born next decades can live up to 150 years

The quest for immortality is the oldest tale in the world. It's the oldest written story known to historians as the Gilgamesh Age, written for the first time in the Macedonian cuneiform script, some 4,000 years ago in what is modern-day Iraq. In this work King Gilgames looks for a plant [...]
The quest for immortality is the oldest tale in the world. It's the oldest written story known to historians as the Gilgamesh Age, written for the first time in the Macedonian cuneiform script, some 4,000 years ago in what is modern-day Iraq.
In this work, King Gilgamesh demands a plant that would give him eternal life. There is a serpent who steals it. The Fountain of Youth, the philosophical Stone, every civilization has its own version. Human life is short. Old age and death come soon enough. So we dream of ways to avoid them.
For the first time in human history, however, we now seem to be understanding some of the fundamental real processes of aging. And the most incredible we have an idea of how to slow them down, and maybe even cancel these processes altogether.
In the next few decades, we can discover ways that will enable people to live up to their 150th birthday or beyond. Nearly all of the diseases that affect us, from cancer to degeneracy, heart disease, even many infectious diseases like Covid-19 or flu, are very much related to our age.
An effective method to stop aging would eliminate no little human suffering. It would be stupid to bet they won't work over the next 50 years”- says Andrew Still, a computer biologist. Multimiliarder Jeff Bezos, founder of the company “Amazon”, has invested huge amounts of money in the biotechnic company “Altos”, focused on “cell recovery”.
Recently, a study published in “Nature Aging” found that by unactivating certain genes in rats responsible for aging, the aging process can be delayed in times without bringing about any harmful side effects. Another study published in “Aing Cell” revealed something similar. Other studies in recent years have extended life spans to various animals, from round worms to fruit flies and rats.
The researchers took two main items. First, it encouraged cells to return to a previous form. The cells in our body, besides our sperm and eggs, all have the same genome. DNA in kidney cells is the same as the DNA of brain cells or skin cells.
But each of them does different things. So each cell activates only a certain set of genes.
But all the cells in our body are originally derived from just two cells, sperm and eggs that created us. To produce all these hundreds of different types of cells, at the beginning of our development our bodies had many non - specialized cells that had the potential to become anything - part of a kidney, a brain, or a skin.
These “stem-cells are the way our body makes its various parts specialized. About 15 years ago, scientists discovered that they could guide the activism of a group of four genes in each cell. This could cause this cell to become a stem cell. The genes are known as “Alphas Yamanaka”, under the name of Japanese Nobel Prize-winning biologist Shinya Yamanaka.
Another recent discovery is that cells have a very precise biological clock inside them. DNA is made up of a long chain of smaller molecules known as nucleotides. There are 4: C (citoline), A (adenine), G (Guana) and T (train). All the complexity of life comes from their rankings in different ranks.
As we grow up, the C's change slightly after they get a small chemical marker called the methyl group. Reading the number of cytos in your genome that have been methylized shows someone's age within three years. Wolf Reick, a researcher at Cambridge's Babrahham Institute, told me a few years ago that this is the most accurate biomarketer of aging we know.
And Activating the “-facts of Yamanaka” into a cell for a long time, it converts to zero methy time. But what is not yet clear, at least so far, is whether methyling represents the cause of aging, or is simply a reading of it. But whatever it is, he's useful.
What world study researchers did at “Nature Aging” was genetic engineering of mice, so that “the Yamanaka” sectors could be activated only in the presence of a particular drug, the doxicilin antibiotic. Then they tried to give the doxiciklin mice into the next dose.
They discovered that the rats, who were disparately given the drug, probably for twice every seven days their DNA methyl time went back. So they were younger. The dream is the realization of this intervention in humans. And there are obstacles here.
First, the rats on which these studies were conducted are genetically modified. The genetic engineering is essentially very difficult in people”- says Professor Jurg Bahler, geneticist at the University College Institute of London on healthy aging. Even if allowed, editing embryo DNA wouldn't be useful to people alive today.
But this is not an insurmountable challenge. In recent years, the development of <x0 genetic therapy” has given the sick hope from genetic diseases by modified the genetic code in their cells. This process is much more difficult because it requires the editing of DNA, not in 1 or 2 cells, but in millions or billions, using a virus to insert the new code into cells.
But it's working. People have been treated for dramous anemia, congenital blindness, and other terrible diseases.
Taking a cut.












