What are the causes of depression?

The causes of depression remain unknown to science.

It will likely result from a combination of genetic, biochemical, environmental and psychological factors. Trauma, the loss of a loved one, a difficult relationship, or a stressful situation that numbs the ability to cope can cause a depressive episode. Subsequent depressive episodes could occur with or without an apparent trigger, Kosovo Preess broadcast.

Research with brain image technologies, such as magnetic resonance imaging (MRI), shows that the brain of depressed people seems different from that of those without depression. Parts of the brain responsible for humor, thought, sleep, appetite, and behavior seem to function abnormally. It is not clear what visible changes in the brain may be the cause of depression and what the effects are.