The discovery of the century: Nicotine Addict

It is thought that finding can lead to a drug that will help combat nicotine addiction.

When addiction develops, the same neurons that tell the brain not to consume cigarettes also tell him that it should continue smoking to avoid the stress it has after giving up, writes the Daily Mail.

This second voice exceeds cigarette disgust, which makes it more difficult to fight dopamine effects and stimulates people to smoke more.

Scientists at the University of Toronto say that this knowledge can help them develop a drug, similar to what already exists to alcoholism, which blocks the pleasure of smoking in which it becomes a refusal.

Nicotine is one that creates dependence, but a addict's relationship with him is far more complex than that of an opioid addict. It gives the brain both signals: Quit smoking and stop smoking.

At the same time, nicotine mimics the shape and activity of acetilcolinis, a neurotransmitter that participates in pleasure as in some addictions, the Kosovas broadcasts.

Scientists have long known that nicotine behaves in these two seemingly contradictory ways, but not how those “fly” into the brain or why addiction seems to easily exceed disgust.

Receptors in the same region of the brain, known as the Ventral Sector area, play an important role in “yield”.

These receptors represent an end to the nerve branch that extends to other distinct areas of the brain and body. Some of these receptors travel to the same places, others travel to different countries. Part of the receptor is connected to dopamine and the other to gamma acid.

Dopamine is a chemical component that has a fine effect on mood and pleasure, but it is also associated with disgust.

The more you smoke, the more you get into pleasure. It's almost like a brain shift and almost a break in signaling, so a impact signaled by dopamine neurons is present now, but it's almost the same with a sense of satisfaction “, said Tarin Grider, who studied nicotine addiction for about ten years.

Nicotine addicts feel better when they smoke, but dopamine excess leads to schizophrenia and Parkinson.

If we exclude those other neurons that make you feel comfortable smoking, then there is only disgust,” explains Grider.

The other neurons are related to gamma-amatobuteric acid, which is a counterweight to neurotransmitters involved in stress. Grider and her team now know what medicine they need. Now they just have to do one.

“We will target gamma-aminbuteric acid receptors so that nobody feels satisfied while smoking, but we have to be sure it won't affect other pleasures”, said Grider.