The strongest antibiotics are found in the human body, to be used in the future

The strongest antibiotics are found in the human body, to be used in the future

A new generation of antibiotics can come from molecules that naturally occur in the human organism as an enzyme that helps to digest. In fact, these substances are capable of killing bacteria such as Salmonella and the Kollical Esceric and can be modified to combat superbacteria that are resistant to [...]

In fact, these substances are capable of killing bacteria such as Salmonella and the Koli Esceric and can be modified to combat drug - resistant superbacteria.

This find has been reached by a search published in “ACS Synthetic Biology” and implemented by Alberto Di Donato and Eugenio Notomista University's “Federico II” of Naples, and by Cesar de la Fuente Nunez of the Institute of Technology at Massacuset (MIT).

“A series of traditional antibiotics are already ineffective because bacteria have learned to interact with these substances, as a consequence the essential goal is to try to develop a new category of molecules against which bacteria do not know to protect”, said Di Donato.

In researching new weapons against bacteria, biologists and chemists are focusing on some substances produced by the human organism that help the immune system fight infection.

“Yet these substances are not powerful enough to operate alone. So the idea is to individualize those that manage to combat bacteria so that synthetic biology can then be used to modified and to make it more powerful”, says De la Fuente Nunez. To that end, researchers have developed a software that enables the analysis of the protein structure to see if we have chemical groups capable of neutralizing bacteria.

This software has identified about 800 of these proteins and has been noted that one of them, present in the stomach, is able to kill at least three types of bacteria, such as Slamonella, E. The col and the Pseudemonas aeruginosa, which can infect the lungs.

Now research will focus on this enzyme, which can become the basis of new antibiotics being produced.

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