Antibiotics of the Future Hidden in the Human Body

A new generation of antibiotics can come from molecules that naturally occur in the human organism as an enzyme that helps to digest.

In fact, these substances are capable of killing bacteria such as Salmonella and the Koli Esceric and can be modified to combat drug - resistant superbacteria.

This find has been reached by a search published in “ACS Synthetic Biology” and implemented by Alberto Di Donato and Eugenio Notomista University's “Federico II” of Naples, and by Cesar de la Fuente Nunez of the Institute of Technology at Massacuset (MIT).

“A series of traditional antibiotics are already ineffective because bacteria have learned to interact with these substances, as a consequence the essential goal is to try to develop a new category of molecules against which bacteria do not know to protect”, said Di Donato.

In researching new weapons against bacteria, biologists and chemists are focusing on some substances produced by the human organism that help the immune system fight infection.

“Yet these substances are not powerful enough to operate alone. So the idea is to individualize those that manage to combat bacteria so that synthetic biology can then be used to modified and to make it more powerful”, says De la Fuente Nunez.

To that end, researchers have developed a software that enables the analysis of the protein structure to see if we have chemical groups capable of neutralizing bacteria.

This software has identified about 800 of these proteins and has been noted that one of them, present in the stomach, is able to kill at least three types of bacteria, such as Slamonella, E. The col and the Pseudemonas aeruginosa, which can infect the lungs.

Now research will focus on this enzyme, which can become the basis of new antibiotics being produced.

Pessimism burning is in the brain

Pessimism burns in the brain. This is the part called the knot related to negative decisions.

The study, published in the magazine Neuron, signed by the group at “Massachets Institute of Technology” (MIT), run by Ken-Ichi Amemor and Satoko Amemor, can help to understand the origin of depression and anxiety in persons with neuropsytric problems and to develop new possible treatments.

The study is part of a research project in nervous circles that control emotions, especially those related to the analysis of the costs and advantages at the polls.

Researchers have found in lab rats that stimulating this part of the brain creates a paralyzing effect, contracting their ability to make decisions.

A situation that lasts a day after this part of the brain is stimulated.

“We have noted that stimulating the caudate core makes the animals more reluctant by pushing them to overestimate spending on the benefits they may have on their actions”, researchers point out.

The next step in the study will be assessed by imaging techniques, magnetic resonance, caudate core activity, and links to the lymphical system, the cradle of emotions, people suffering from depression and anxiety.

Success is written in the genes!

The promises for a successful life are written in a small set of genes, which normally is not enough to become successful persons, but certainly enable you to have an advantage, regardless of context and special affiliation, according to a analysis developed by over 20,000 people between the United States, Britain and New Zealand, published in the American Academy of Sciences magazine (PNAS) by an international group headed by Duke University, U.S.A.

This study has enabled a group of genes to intervene in social climbing. The weight of successful genetic variants is translated into a setting, which is then used as a parameter to compare different individuals based on the achievements made in life (for example, educational level, professional career or income).

The results show that people with the highest score are the most successful, regardless of social status. High - score subjects tend to have better results in parenting, even brothers, beyond the social context in which they grew up.

The genes of success act like an engine that activates social climbing, although their postponement is too limited. In fact, they impact up to 4% on social mobility.

The effect of aspirin depends on a patient's weight

The effect of a daily aspirin on preventing certain health problems depends on the body weight of the user, according to a study published in the magazine “Lancet”

The results of this study, including the data of 10 random studies, show that the dose of aspirin and the weight of a patient had a marked impact on the efficiency of the drug.

A daily dose of aspirin between 75 and 100 milligrams reduces the risk of cardiovascular difficulties in people who weigh up to 70 pounds [70 kg].

This effect, however, is not achieved in those weighing over 70 pounds [70 kg].

A daily dose between 325 and 500 milligrams is needed for risking cardiovascular difficulties.