Science takes men out of play, reproduction is achieved in laboratory conditions

Chinese scientists have managed to make it possible in the laboratory conditions without men. In a major discovery in the field of epigenetics, scientists at the Chinese Academy of Sciences seem to have changed the current method of mammal reproduction.

They managed to cross the barrier of a male bonding with a female for the sexual reproduction of mammals, using 210 embryos to create 29 live, healthy mice from two mothers without fathers.

We have always been curious why mammals are subject only to sexual reproduction”, one of the authors of the study says. Or sperm - free reproduction is common among insects, fish, and reptiles but not mammals

The team focused on about 100 genes that are activated when they come from both parents, but rely on each other for proper development. However, using only the genetic material obtained from two female mice, the team neutralised several important sequences in the DNA of the embryoal stem cells, using Crispr-Cass9, a tool used for genetic divide.

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Rats who came to life in this new way reached maturity and were reproduced according to the usual method.

Although it may be considered a major step in fertilization by parents of the same sex, current techniques still far from being perfect: only 29 live mice have been produced by 210 embryos. In addition, this success was not achieved in the case of two male mice - none of them survived more than 48 hours.

The technique must be deepened through new studies to see if it can be applied to people. However, this experiment is important because it can shed light on the way to revealing new causes of infertility. https://w.cell.com/cell-sem-cell/fulltext/ S1934-5909 Tread is published in “Cell”. /tema/