Are there more boys or girls born after fertilization in vitro (IVF)?

Are there more boys or girls born after fertilization in vitro (IVF)?

Scientists find that the rate of embryo development, selection algorithms, and even artificial intelligence can affect the gender composition of babies born through IVF when couples plan to have children, most believe that chances for girls or boys are equal to 50:50. However, in cases where pregnancy is achieved through fertilization [...]

When couples plan to have children, most believe that chances for a girl or boy are equal to 50:50. However, in cases where pregnancy is achieved through in vitro fertilization (IVF), the possibility of a baby being a boy is greater.

Researchers have found that male embryos develop a little faster, so they are chosen more often to move to the womb. That's why the chances of a couple making IVF having a boy amount to 56 out of 100 cases.

When we link the fastest development to the best quality, we unconsciously select male embryos”, explains Dr. Helen O'Neill, fertility specialist at London University. “The devices we use to select embryos favour the male gender”.

Why male embryos are the fastest “”

Male embryos carry X and Y chromosomes, while feminine ones carry two X chromosomes. This extra X to female embryos brings an additional process of “reactivating” of an X chromosome to maintain genetic balance, the process that requires more energy. Hence, female embryos develop more slowly in their early stages. As a result, in IVF, where embryos are selected according to the rhythm and order of development, male embryos have a small advantage, which increases the likelihood of being chosen for transfer, the Daily Mail notes.

Artificial intelligence can also favor male embryos

Dr. O'Neill and her team have conducted a study of 1,300 embryos, whose gender was previously known through genetic testing. The embryos have been praised by doctors and two artificial intelligence systems (AI), which use “time-lapse” of embryo development.

The results showed that:

  • When doctors made the selection, 69% of male embryos were estimated to be best quality “, compared to 57% of female embryos.
  • One of AI's systems also showed slight tendencies toward male embryos, while the other was neutral. Although differences are minor, they are enough to create a slight gender trend in embryo selection statistics.
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